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The Inorganic Chemistry Laboratory (ICL), which incorporates
the Chemical Crystallography Laboratory, is justly famous for its distinguished
history in research. Pioneering work in coordination chemistry, organometallic
chemistry, radiochemistry, the chemistry of the solid state and the X-ray
structure determinations of biomolecules laid the foundations of modern
inorganic chemistry. The tradition continues.
The ICL has a uniquely wide range of research ranging
from synthetic organometallic main group and coordination chemistry, through
solid state chemistry and catalysis to the study of metalloenzymes:
Bioinorganic Chemistry: The study of metal centres
and clusters in biological systems: electron transfer; electrochemistry
of proteins and enzymes; the design of biosensors for medicine; and the
catalytic activity of haem proteins.
Organometallic Chemistry and Catalysis: Research
focuses on transition metal compounds; and the mechanisms of homogeneous
catalysis in solution, e.g. of hydroformylation, asymmetric synthesis,
CH activation, O2 activation; heterogeneous oxidation catalysis
by metal oxides. In the last area, interest focuses on the conversion
of CH4 to useful organic chemicals.
Coordination chemistry: macro-cyclic complexes
(with crown ethers etc.), for the modelling of molecular recognition processes
and electron transfer in biological systems, and for the design of new
molecular sensors and redox catalysts; also radio-pharmaceuticals for
imaging and therapeutic applications.
Electrical, magnetic and optical properties of solids:
including metal oxides, sulphides and nitrides, intercalation compounds
and organometallic materials. Magnetic ordering and magneto-resistance
are currently major interests, as are non-linear optical properties. The
investigations employ, e.g., squid magnetometry, neutron diffraction,
PES and optical spectroscopy, together with complementary theoretical
studies.
Molecular studies: exploratory synthetic work,
mainly in organometallic, supramolecular, nano technology and main group
chemistry; characterisation of structure, bonding and reactivity by single-crystal
X-ray crystallography, NMR, infrared and Raman spectroscopy, PES, etc.;
investigation of reactive intermediates and other transient molecules;
associated theoretical studies.
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