In-silico Screening for Anthrax Toxin Inhibitors

Images of the anthrax toxin protective antigen heptamer. Images are either from the top or side, coloured to show various structural relationships of the seven protein units. In each image is also a gold molecule (our target drug) binding to the protein and thereby blocking the binding of the lethal factor to the heptamer. We would like to thank Carlo Petosa (EMBL Grenoble Outstation, France) for kindly giving us the structure of the PA heptamer.

 

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