Vitamin B1, Thiamine, aneurine, releases energy from carbohydrate, alcohol and fat. It is an anti-neuritic factor, the absence of which from the diet of animal leads to the disease beri-beri, and from that of mammals and birds to polyneurtics, the most fundamental symptoms of which is general nervous atrophy.
Thiamine pyrophosphate. The biochemically active derivative of thiamine, the pyrophosphate ester of thiamine. It is coenzyme which is concerned in a number of important metabolic process. These include the decarboxylation of alpha-oxoglutaric acid in citric acid cycle and the conversion of alanine, via pyruvic acid to acetyl coenzyme A. The actions of thiamine pyrophosphate are all similar in that they involve the intermediacy of the active aldehyde attached (as carbinol substituents) to the thiaole ring at position 2.
Good sources of sources Vitamin B1 are yeast eggs and germ of cereals. It is not present in polished rice and other highly purified cereal products. The minimum required daily dose is believed to be about 2 mg.
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Vitamin B1 -3D structure |
Vitamin B1 -2D structure - It is isolated as the chloride, C12H18Cl2H4OS.H20 |
