Publications


Reviews
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Chemistry of beta-lactams
Westwood NJ, Schofield CJ
Royal Society Of Chemistry, Specialist Periodical Reports, Amino Acids, Peptides And Proteins, 1995, 26, Chapter 6, 330-391.


Molecular mechanism of the multifunctional enzyme L-delta(alpha-L-aminoadipoyl)-L-cysteinyl-D-valine (ACV) synthetase
Shiau C-Y, Byford MF, Baldwin JE, Schofield CJ
Biochemical Society Transactions, 1995, 23, P.S 629.


Expression, purification and characterization of 1-aminocyclopropane-1-carboxylate oxidase from tomato in Escherichia-coli
Zhang Z-H, Schofield CJ, Baldwin JE, Thomas P, John P
Biochemical Journal, 1995, 307, 77-85.


Delta-L-(Alpha-Aminoadipoyl)-L-Cysteinyl-D-Valine Synthetase - Isolation Of L-Cysteinyl-D-Valine, A Shunt Product, And Implications For The Order Of Peptide-Bond Formation
Shiau C-Y, Baldwin JE, Byford M F, Schofield CJ
FEBS Letters, 1995, 373, 303-306.


Reaction of Ruppert's reagent (TMS-CF3) with oxazolidinones - synthesis of protected alpha-amino trifluoromethylketones
Walter MW, Adlington RM, Baldwin JE, Chuhan J, Schofield CJ
Tetrahedron Letters, 1995, 36, 7761-7764.


Crystal-structure of isopenicillin N-synthase is the first from a new structural family of enzymes
Roach PL, Clifton IJ, Fulop V, Harlos K, Barton G J, Hajdu J, Andersson I, Schofield CJ, Baldwin JE
Nature, 1995, 375, 6533, 700-704.


Crystallization and preliminary-x-ray diffraction studies on recombinant isopenicillin-N synthase from Aspergillus-nidulans
Roach PL, Schofield CJ, Baldwin JE, Clifton IJ, Hajdu J
Protein Science, 1995, 4, 1007-1009.


Analysis of the in-vitro inactivation of 1-amino-cyclopropane-1-carboxylic acid oxidase (ACC oxidase) in the presence of substrates and cofactors
Barlow JN, Schofield CJ
FASEB Journal, 1995, 9, No. 6, P.A1492.


Cleavage of the 5-amino-5-carboxy-2-oxapentanoyl side-chain from enzymatically synthesized penicillins and cephalosporins
Baldwin JE, Davis S C, Forrest A K, Schofield CJ
Bioorganic & Medicinal Chemistry Letters, 1995, 5, 2507-2512.


Delta-L-(alpha-aminodipoyl)-L-cysteinyl-D-valine synthetase - the order of peptide-bond formation and timing of the epimerization reaction
Shiau C-Y, Baldwin JE, Byford M F, Sobey W , Schofield CJ
FEBS Letters, 1995, 358, 97-100.


Does the observation of noncovalent complexes between biomolecules by electrospray-ionization mass-spectrometry necessarily reflect specific solution interactions
Aplin RT, Robinson CV, Schofield CJ, Westwood NJ
Chemical Communications, 1994, 2415-2417.


Porcine pancreatic elastase: beta and gamma lactam inhibitors
Aplin RT, Robinson C V, Schofield CJ, Westwood NJ
Protein Science, 1995, 386-T, 130.


Inhibition of TEM-2 beta-lactamase by clavulanic acid: direct observation of intermediates
Brown R P, Aplin RT, Schofield CJ
Protein Science, 1995, 638-M, 174.