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MAGNETIC RESONANCE
Dr. C.R. Timmel
Michaelmas Term – Third Year
The physics of magnetic resonance: the magnetic moment, the
spin quantum number, the gyromagnetic ratio, space quantization,
the resonance condition, the vector model, populations and
bulk magnetization, selection rules, the origin of shielding,
diamagnetic and paramagnetic shielding, neighbouring group
anisotropy, ring current effects, electronic effects, intermolecular
interactions.
Spin-Spin Coupling, energy level considerations, labeling
of spin systems, AMX systems, AX2 systems, AX3 systems, AXn
systems, coupling to spins with I>1/2, limits of the simple
splitting rules, magnetic equivalence, the origin of the roof
effect, strong coupling effects, discussion of Fermi contact
interaction and dipole-dipole interactions.
Experimental methods: continuous wave and pulsed NMR, introduction
of Free Induction Decay (FID) and Fourier Transformation for
simple FIDs.
The rotating frame, linear and circularly polarized fields,
NMR as a coherence phenomenon.
Spin relaxation, spin lattice and spin-spin relaxation, the
rotational correlation time and the spectral density function,
spin relaxation and the vector model, measurement of relaxation
times, the inversion recovery experiment, the spin echo experiment.
Chemical Exchange, symmetrical exchange, slow and fast exchange
limits, intermediate exchange, unsymmetrical two-site exchange.
A short introduction to two-dimensional NMR: Correlated Spectroscopy
(COSY), Exchange Spectroscopy (EXSY) and Nuclear Overhauser
Spectroscopy (NOESY).
Reading:
Mostly: P.J. Hore, Nuclear Magnetic Resonance
P.J. Hore, J.A. Jones, S. Wimperis, NMR: The Toolkit
H. Friebolin: One- and Two-dimensional NMR
H. Günther, NMR Spectroscopy
A. Carrington and A.D. McLachlan , Introduction to Magnetic
Resonance
R. Freeman, A Handbook of nuclear magnetic resonance
R.R. Ernst, G. Bodenhausen and A. Wokaun, Principles of Nuclear
Magnetic Resonance in One and Two Dimensions
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