• This reaction is an example of electrophilic aromatic substitution.
  • The reaction does not work when one uses phenolic or amino aromatic starting materials, as a complex is formed with the Lewis Acid AlCl3.


  • References:
  • Tanaka M.; Fujiwara M.; Ando H.; J. Org. Chem., 1995, Volume 60, Issue 7, 2106-2111
  • Tanaka M.; Fujiwara M.; Xu Q.; Souma Y.; Ando H.; Laali K.K.; J. Am. Chem. Soc., 1997, Volume 119, Issue 22, 5100-5105