Department of Chemistry

Department of Chemistry University of Oxford

Engineering new signalling networks to produce crops that need less fertiliser

Engineering new signalling networks to produce crops that need less fertiliser

An interdisciplinary research collaboration between the Universities of Oxford and Cambridge has engineered a novel synthetic plant-microbe signalling pathway that could provide the foundation for transferring nitrogen fixation to cereals.

Published in Nature Communications today, the team of plant scientists, microbiologists and chemists used synthetic biology techniques to design and then engineer a molecular dialogue between plants and the bacteria surrounding their roots in a zone called the rhizosphere. This synthetic signalling system could be a vital step towards successfully engineering nitrogen-fixing symbiosis in non-legume crops like wheat and maize.

Further work in the Poole, Oldroyd and Conway laboratories will focus on how plants can control key processes in root bacteria such as nitrogen fixation, phosphate solubilisation and plant growth promotion. This opens up the world of the bacterial microbiome and its diverse metabolism to control by plants and in particular the cereals. It is likely to be a key component in attempts to engineer nitrogen fixation into cereals.
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