Publications

Some of my recent publications (journal papers and books) are listed below. Most of these papers are produced from collaborations with the various research groups within the department. More information regarding the research activities of these groups may be found on the Chemistry staff web pages.

Books

 

 

 

 

 

 

 Introduction to Organic Spectroscopy
L. M. Harwood and T. D. W. Claridge, OUP, Oxford, 1997.

1999: Available in Japanese

This book is an undergraduate text book produced for Oxford Unversity Press as part of the Oxford Chemistry Primer series.

 
 

 

 

 

 


 

 High-Resolution NMR Techniques in Organic Chemistry
T. D. W. Claridge, Pergamon, Oxford, 1999.

This is a new graduate/advanced undergraduate level text produced for Elsevier Science as part of the Tetrahedron series.

This should also be well suited to chemists and spectroscopists in industry.

2003: Reprinted [with corrections]

2004: Available in Japanese

 
 		 High-Resolution NMR Techniques in Organic Chemistry (2nd Edition)
T. D. W. Claridge, Elsevier, Oxford, 2009

A fully updated and extended edition of the widely acclaimed first edition.

 

 

 
 		 Multidimensional NMR Methods for the Solution State
G. A. Morris and J. W. Emsley (Eds), Wiley, 2010

This is collection of articles describing solution state NMR methods.

I have contributed Chapter 16 on TOCSY.

 

Papers

2011 

113) A systematic study of the solid state and solution phase conformational preferences of b-peptides derived from C(3)-alkyl substituted transpentacin derivatives
Elin Abraham, Timothy D.W. Claridge, Stephen G. Davies , Barbara Odell, Paul M. Roberts, Angela J. Russell, Andrew D. Smith, Lorna J. Smith, Helen R. Storr, Miles J. Sweet, Amber L. Thompson, James E. Thomson, George E. Tranter, David J. Watkin, Tet. Asymm., 2011, 22, 69-100. [DOI:10.1016/j.tetasy.2010.12.007]

112) Asparagine and aspartate hydroxylation of the cytoskeletal Ankyrin family is catalysed by Factor-Inhibiting Hypoxia-Inducible Factor
Ming Yang, Wei Ge, Rasheduzzaman Chowdhury, Timothy D. W. Claridge, Holger B. Kramer, Bernhard Schmierer, Michael A. McDonough, Lingzhi Gong, Benedikt M. Kessler, Peter J. Ratcliffe, Mathew L. Coleman, and Christopher J. Schofield, J. Biol. Chem., 2011, 286, 7648-7660. [DOI:10.1074/jbc.M110.193540]

111)  The 2-Oxoglutarate Dependent Oxygenase JMJD6 Catalyses Oxidation of Lysine Residues to give 5S-Hydroxylysine Residues

Monica Mantri, Nikita D. Loik, Refaat B. Hamed, Timothy D. W. Claridge, James S. O. McCullagh, Christopher J. Schofield, ChemBioChem, 2011, 12, 531-534. [DOI: 10.1002/cbic.201000641]

110) Tuning the cavity of cyclodextrins: altered sugar adaptors in protein pores
Wen-Wu Li, Timothy D.W. Claridge, Qiuhong Li, Mark R. Wormald, Benjamin G. Davis and Hagan Bayley,  J. Am. Chem. Soc., 2011, 133, 1987-2001. [DOI: 10.1021/ja1100867]

109) Vernier Templating and Synthesis of a 12-Porphyrin Nano-ring
Melanie C. O’Sullivan, Johannes K. Sprafke, Dmitry V. Kondratuk, Corentin Rinfray, Timothy D. W. Claridge, Alex Saywell, Matthew O. Blunt, James N. O’Shea, Peter H. Beton, Marc Malfois & Harry L. Anderson, Nature, 2011, 469, 72-75. [DOI:10.1038/nature09683]

2010 

108) Structural and Mechanistic Studies on g-Butyrobetaine Hydroxylase
Ivanhoe K.H. Leung, Tobias J. Krojer, Grazyna T. Kochan , Luc Henry, Frank von Delft, Timothy D. W. Claridge, Udo Oppermann, Michael A. McDonough, and Christopher J. Schofield, Chemistry & Biology, 2010, 17, 1316-1324. [DOI:10.1016/j.chembiol.2010.09.016]

107) Studies on the reaction of glutathione and formaldehyde using NMR
Richard J. Hopkinson, Philippa S. Barlow, Christopher J. Schofield and Timothy D. W. Claridge, Org. Biomol. Chem., 2010, 8, 4915-4920.  [DOI: 10.1039/C0OB00208A]

106) A systematic study of the solid state and solution phase conformational preferences of b-peptides derived from transpentacin
Elin Abraham, Callum W. Bailey, Timothy D. W. Claridge, Stephen G. Davies, Kenneth B. Ling, Barbara Odell, Thomas L. Rees, Paul M. Roberts, Angela J. Russell, Andrew D. Smith, Lorna J. Smith, Helen R. Storr, Miles J. Sweet, Amber L. Thompson, James E. Thomson, George E. Tranter, David J. Watkin, Tet. Asymm., 2010, 21, 1797-1815. [DOI:10.1016/j.tetasy.2010.06.001]

105) Structure and reactivity of bicyclic methylene aziridines prepared by intramolecular aziridination of allenes
Jeremy Robertson, George C. Feast, Louise V. White, Victoria A. Steadman (n´ee Doughty) and Timothy D. W. Claridge, Org. Biomol. Chem., 2010, 8, 3060-3063 [DOI: 10.1039/c003693e]

104) Monitoring the Activity of 2-Oxoglutarate Dependent Histone Demethylases by NMR Spectroscopy: Direct Observation of Formaldehyde
Richard J. Hopkinson, Refaat B. Hamed, Nathan R. Rose, Timothy D. W. Claridge, and Christopher J. Schofield, ChemBioChem, 2010, 11, 506-510. [DOI: 10.1002/ cbic.200900713.]

103) Carboxymethylproline synthase catalysed syntheses of functionalised N-heterocycles
Refaat B. Hamed, Jasmin Mecinovic , Christian Ducho, Timothy D. W. Claridge and Christopher J. Schofield, Chem. Commun., 2010, 46, 1413 – 1415. [DOI: 10.1039/b924519g]

102) Group epitope mapping considering relaxation of the ligand (GEM-CRL): Including longitudinal relaxation rates in the analysis of saturation transfer difference (STD) experiments
Sebastian Kemper, Mitul K. Patel, James C. Errey, Benjamin G. Davis, Jonathan A. Jones, Timothy D. W. Claridge, J. Magn. Reson., 2010, 203, 1-10. [DOI: 10.1016/j.jmr.2009.11.015]

 

101) Using NMR Solvent Relaxation to Investigate Metalloenzyme-Ligand Binding Interactions

Ivanhoe K. H. Leung, Emily Flashman, Kar Kheng Yeoh, Christopher J. Schofield and Timothy D. W. Claridge, J. Med. Chem., 2010, 53, 867-875. [DOI: 10.1021/jm901537q]

2009

100) Sulfate anion templated synthesis of a triply interlocked capsule
Yitong Li,  Kathleen M. Mullen, Tim Claridge, Paulo J. Costa, Vitor Felix, and Paul D. Beer, Chem. Comm., 2009, 7134-7136 [DOI: 10.1039/ b915548a]

99) Saturation Transfer Difference NMR reveals functionally essential kinetic differences for a sugar binding repressor protein
Ignacio Pérez-Victoria, Sebastian Kemper, Mitul K. Patel, John Edwards, James C. Errey, Lucia F. Primavesi, Matthew J. Paul, Timothy D. W. Claridge, and Benjamin G. Davis, Chem. Comm., 2009, 5862-5864 [DOI: 10.1039/b913489a]

98) A C-linked Glycomimetic in the Gas Phase and in Solution: Synthesis and Conformation of the Disaccharide Mana(1,6)-C-ManaOPh.
Ludovic Drouin, E. Cristina Stanca-Kaposta, Priptal Saundh, Antony J. Fairbanks, Sebastian Kemper, Timothy D. W. Claridge, and John P. Simons, Chem. Eur. J., 2009, 15, 4057-4069. [DOI: 10.1002/chem.200802179]

97) Evidence that Thienamycin Biosynthesis Proceeds via C-5 Epimerization: ThnE Catalyzes the Formation of (2S,5S)-trans- Carboxymethylproline.
Refaat B. Hamed, Edward T. Batchelar, Jasmin Mecinović, Timothy D. W. Claridge and Christopher J. Schofield, ChemBioChem, 2009, 10, 246-250 [DOI: 10.1002/cbic.200800652]

96) Anatomy of a Simple Acyl Enzyme Intermediate in Enzyme Catalysis - Combined Biophysical and Modelling Studies on Ornithine Acetyl Transferase
Aman Iqbal, Ian. J. Clifton, Maria Bagonis, Nadia J. Kershaw, Carmen Domene, Timothy D. W. Claridge, Christopher W. Wharton & Christopher. J. Schofield, J. Am. Chem. Soc, 2009, 131, 749-757. [DOI: 10.1021/ja807215u].

2008

 95) Highly (E)-Selective Wadsworth-Emmons Reactions Promoted by Methylmagnesium Bromide
Timothy D. W. Claridge, Stephen G. Davies, James A. Lee, Rebecca L. Nicholson, Paul M. Roberts, Angela J. Russell, Andrew D. Smith, and Steven M. Toms, Org.Lett, 2008, 10, 5437-5440. [DOI: 10.1021/ol802212e]

 94) “Pure by NMR”?
Timothy D. W. Claridge, Stephen G. Davies, Mario E. C. Polywka, Paul M. Roberts, Angela J. Russell, Edward D. Savory, and Andrew D. Smith, Org.Lett, 2008, 10, 5433-5436. [DOI: 10.1021/ol802211p]

 93) Thioester Hydrolysis and C-C Bond Formation by the Crotonase Superfamily Enzyme Carboxymethylproline Synthase
 Edward T. Batchelar, Refaat B. Hamed, Christian Ducho, Timothy D. W. Claridge, Mariola J. Edelmann, Benedikt Kessler and Christopher J. Schofield, Angew. Chem. Int. Ed. Engl., 2008, 47, 9322-9325.[ DOI: 10.1002/anie.200803906]

 92) A Two-Directional Approach to Enantiopure 1,4-Difluoro- Cyclohexenes: Synthesis of Difluorinated Cyclitol Analogues
Sophie Purser, Timothy D. W. Claridge, Barbara Odell, Peter R. Moore, and Véronique Gouverneur, Org. Lett., 2008, 10, 4263-4266.  [DOI: 10.1021/ol8017402]

 91) Ammonium-directed dihydroxylation of 3-aminocyclohex-1-enes: development of a metal-free dihydroxylation protocol
Caroline Aciro, Timothy D. W. Claridge, Stephen G. Davies, Paul M. Roberts, Angela J. Russell and James E. Thomson, Org. Biomol. Chem., 2008, 6, 3751-3761, [DOI: 10.1039/b808811j]

 90) Synthesis and Conformational Analysis of Cyclic Analogues of Inverse g-Turns
Morakot Kaewpet, Barbara Odell, Michael A. King, Biswadip Banerji, Christopher J. Schofield  and Timothy D. W. Claridge, Org. Biomol. Chem., 2008, 6, 3476-3485,   [DOI: 10.1039/b808954j]

 89) Amylose-wrapped luminescent conjugated polymers
Michael J. Frampton, Timothy D. W. Claridge, Gianluca Latini, Sergio Brovelli, Franco Cacialli and Harry L. Anderson,  Chem. Commun., 2008, 2797-2799, [DOI: 10.1039/b803335h]

 88) Secondary structural investigations into homo-oligomers of d-2,4-cis oxetane amino acids
Timothy D. W. Claridge, Beatrice Lopez-Ortega, Sarah F. Jenkinson and George W. J. Fleet, Tet. Asymm, 2008, 19, 984-988. [doi:10.1016/j.tetasy.2008.03.029]

 87) Oxetane amino acids: synthesis of tetrameric and hexameric carbopeptoids derived from L-ribo 4-(aminomethyl)-oxetan-2-carboxylic acid
Beatrice Lopez-Ortega, Sarah F. Jenkinson, Timothy D. W. Claridge and George W. J. Fleet, Tet. Asymm, 2008, 19, 976-983. [doi:10.1016/j.tetasy.2008.03.030]

86) Stereospecific anti SE2’ Fluorination of Allenylsilanes: Synthesis of Enantioenriched Propargylic Fluorides
Laurence Carroll, Samantha McCullough, Tom Rees, Timothy D. W. Claridge and Véronique Gouverneur, Org. Biomol. Chem, 2008, 6, 1731-1733. [ DOI: 10.1039/b803888k]

 85) From Disulfide- to Thioether-Linked Glycoproteins
Gonçalo J. L. Bernardes , Elizabeth J. Grayson , Sam Thompson , Justin M. Chalker, James C. Errey , Farid El Oualid, Timothy D. W. Claridge, Benjamin G. Davis, Angew. Chem. Int. Ed. Engl., 2008, 47, 2244-2247. [DOI: 10.1002/anie.200704381 ]

84) Swarm formation in the desert locust Schistocerca gregaria: isolation and NMR analysis of the primary maternal gregarizing agent
Gabriel A. Miller, M. Saiful Islam, Timothy D. W. Claridge, Tim Dodgson and Stephen J. Simpson, J. Exptl. Biol., 2008, 211, 370-376. [doi:10.1242/jeb.013458]

83) Self-assembly of Ligands Designed for the Building of a New Type of [2x2] Metallic Grid. Anion Encapsulation and Diffusion NMR Spectroscopy.
Blanca Manzano, Félix Jalón, Isabel Ortiz, M. Laura Soriano, Felipe Gomez de la Torre, José Elguero, Miguel Maestro, Kurt Mereiter, Tim D. W. Claridge, Inorganic Chemistry, 2008,  47,  413-428. [DOI: 10.1021/ic701117a]

2007

82) Solid-Phase Synthesis of Oligo(Phenylene Ethynylene) Rotaxanes.
Heather W. Daniell, Eric J. F. Klotz, Barbara Odell, Tim D. W. Claridge and Harry L. Anderson, Angew. Chem. Int. Ed. Engl., 2007, 46, 6845-6848.

81) Formation of a chiral center and pyramidal inversion at the single molecule level.
Seong-Ho Shin, Mackay B. Steffensen, Tim D. W. Claridge and Hagan Bayley, Angew. Chem. Int. Ed. Engl., 2007, 46, 7412-7416

80) Inhibition of mycobacterial arylamine N-acetyltransferase contributes to anti-mycobacterial activity of Warburgia salutaris.
Vukani Eliya Madikane, Sanjib Bhakta, Angela J. Russell, William E. Campbell, Timothy D. W. Claridge, B. Gay Elisha, Stephen G. Davies, Peter Smith and Edith Sim, Biooorg. Med. Chem., 2007, 15, 3579-3586.

79) Homochiral carbon branched piperidines from carbon branched sugar lactones: 4-C-methyl-deoxyfuconojirimycin (DFJ) and its enantiomer—removal of glycosidase inhibition.
David J. Hotchkiss, Atsushi Kato, Barbara Odell, Timothy D. W. Claridge and George W. J. Fleet, Tet. Asymm., 2007, 18, 500–512.

78) Metal-driven ligand assembly in the synthesis of cyclodextrin [2] and [3]rotaxanes
Andrew G. Cheetham, Timothy D. W. Claridge and Harry L. Anderson, Org. Biomol. Chem., 2007, 5, 457-462.

2006

77) Homo and hetero-[3]rotaxanes with two p-systems clasped in a single macrocycle
E. J. F. Klotz, T. D. W. Claridge, and H. L. Anderson, J. Am. Chem. Soc., 2006, 128, 15374-15375.

76) Sequential Desymmetrization-Fluorination: Enantioselective Synthesis of Fluorinated Cyclitols
 Sophie Purser , Barbara Odell, Timothy D. W. Claridge, Peter R. Moore, Véronique Gouverneur, Chem. Eur. J., 2006, 12, 9176-9185.

75) Endohexosaminidase M: Exploring and Exploiting Enzyme Substrate Specificity
Thomas W. D. F. Rising, Timothy D. W. Claridge, James W. B. Moir, and Antony J. Fairbanks, Chem. BioChem., 2006, 7, 1177-1180.

74) Synthesis of N-glycan oxazolines: donors for endohexosaminidase catalysed glycosylation
Thomas W. D. F. Rising, Timothy D. W. Claridge, Nicola Davies, David P. Gamblin, James W. B. Moir and Antony J. Fairbanks, Carb. Res., 2006, 341, 1574-1596.

73) Enzymatic Synthesis and Photoswitchable Enzymatic Cleavage of a Peptide-Linked Rotaxane
Andrew G. Cheetham, Michael G. Hutchings, Tim D. W. Claridge, Harry L. Anderson, Angew. Chem. Int. Ed. Engl., 2006, 45, 1596-1599. 

2005

72) On the synthesis of pyrinodemin A. Part 1: The location of the olefin
Stuart P. Romeril, Victor Lee, Jack E. Baldwin and Timothy D. W. Claridge, Tetrahedron, 2005, 61, 1127-1140.

 71) The synthesis of oligomers of oxetane-based dipeptide isosteres derived from L-rhamnose or D-xylose.
Stephen W. Johnson, Sarah F. Jenkinson (née Barker), Donald Angus, Ignacio Pérez-Victoria, Timothy D. W. Claridge, George W. J. Fleet and John H. Jones, J. Peptide Sci., 2005, 11, 303–318.

 70) Helix-forming carbohydrate amino acids
Timothy D. W. Claridge, Daniel D. Long, Christopher M. Baker, Barbara Odell, Guy H. Grant, Alison A. Edwards, George E. Tranter, George W. J. Fleet and Martin D. Smith, J. Org. Chem. 2005, 70, 2082-2090

 69) Synthesis, structure and dynamics of methoxynaphthalene-substituted phospha-ruthenocenes and –ferrocenes
 Duncan Carmichael, Louis Ricard, Nicolas Seeboth, John M. Brown, Timothy D. W. Claridge and Barbara Odell, Dalton Transactions, 2005, 12, 2173 – 2181.

68) Conformational studies of oligomeric oxetane-based dipeptide isosteres derived from L-rhamnose or D-xylose
S. W. Johnson, S. F. Jenkinson (née Barker), I. Pérez-Victoria, A. A. Edwards, T. D. W. Claridge, G. E. Tranter, G. W. J. Fleet and J. H. Jones, J. Peptide Sci., 2005, 11, 517-524.

67) Structural investigations of a lead(IV) tetraacetate-pyridine complex
J. E. H. Buston, T. D. W. Claridge, S. J. Heyes, M. A. Leech, M. G. Moloney, K. Prout and M. Stevenson, Dalton Trans., 2005, 3195-3203.

66) Hypoxia-inducible factor prolyl hydroxylase has a high affinity for ferrous iron and 2-oxoglutarate
Luke A. McNeill, Emily Flashman, Matthew R.G. Buck, Kirsty S. Hewitson, Ian J. Clifton, Gunnar Jeschke, Timothy D. W. Claridge, Dominic Ehrismann, Neil J. Oldham and Christopher J. Schofield. Mol. BioSyst., 2005, 1, 321–324.

2004

65) An unsaturated peptidomimetic assembly derived from a carbohydrate.
Y  -K. Chung, T. D. W. Claridge, G. W.J. Fleet, S. W. Johnson, J. H. Jones, K. W. Lumbard, and A. V. Stachulski, J. Peptide Sci., 2004, 10, 1-7.

64)  Thermal and palladium catalyzed pericyclic rearrangements of a pentaene ester.
Sebastien Bruckner, Jack E. Baldwin, Robert M. Adlington, Tim D. W. Claridge and Barbara Odell, Tetrahedron, 2004, 60, 2785-2788.

63) Conformationally restricted arene intermediates in the intermolecular Heck arylation of vinylarenes.
King Kuok (Mimi) Hii, Timothy D. W. Claridge, Ralf Giernoth and John M. Brown, Adv. Synth. Catal., 2004, 346, 983-988

2003

62) Biomimetic synthesis of the crispatene core.
J. E. Moses, J. E. Baldwin, R. Marquez, R. M. Adlington, T. D. W. Claridge, B. Odell, Org. Lett, 2003, 5, 661-663.

61) Nitrogen inversion as a diastereomeric relay in azasugar synthesis: the first synthesis of Adenophorine
M. A. T. Maughan, I. G. Davies, T. D. W. Claridge, S. Courtney, P. Hay and B. G. Davis, Angew. Chem. Int. Ed. Engl., 2003, 42, 3788-3792.

60) Investigations into the absolute stereochemistry of the marine sponge alkaloid pyrinodemin A
S. P. Romeril, V. Lee, J. E.Baldwin, T. D. W. Claridge and B. Odell, Tetrahedron Lett., 2003, 44, 7757-7761.

59) Enhanced 13C resolution in semi-selective HMBC: a band-selective, constant-time HMBC for complex organic structure elucidation by NMR.
T. D. W. Claridge and I. Pérez-Victoria, Org. Biomol. Chem., 2003, 1, 3632-3634.

58) Bend ribbon-forming tetrahydrofuran amino acids.
M. D. Smith, T. D. W. Claridge, M. S. P. Sansom and G. W. J. Fleet., Org. Biomol. Chem., 2003, 1, 3647-3655.

2002

57) Hypoxia-inducible factor asparaginyl hudroxylase (FIH-1) catalyses hydroxylation at the b-carbon of asparagine-803.
L. A. McNeill, K. S. Hewitson, T. D. Claridge, J. F. Seibel, L. E. Horsfall and C. J. Schofield, Biochem. J., 2002, 367, 571-575.

56) Unidirectional Photoinduced Shuttling in a Rotaxane with a Symmetric Stilbene Dumbbell
Carol A. Stanier, Sara J. Alderman, Tim D.W. Claridge and Harry L. Anderson, Angew. Chem. Int. Ed. Engl., 2002, 41, 1769-1772.

55) Structural basis for the recognition of hydroxyproline in HIF-1alpha by pVHL
Wai-Ching Hon, Michael I. Wilson, Karl Harlos, Timothy D. W. Claridge, Christopher J. Schofield, Christopher W. Pugh, Patrick H. Maxwell, Peter J. Ratcliffe, David I. Stuart & E. Yvonne Jones, Nature, 2002, 417, 975-978.

54) Synthesis of a possible structure of pyrinodemin A.
S. P. Romeril, V. Lee, T. D. W. Claridge and J. E. Baldwin, Tetrahedron Lett., 2002, 43, 327-329.

2001

53) The Intermolecular Asymmetric Heck Reaction: Mechanistic and Computational Studies
K. K. (Mimi) Hii, Timothy D. W. Claridge, John M. Brown, Andrew Smith, and Robert J. Deeth, Helvetica Chimica Acta, 2001, 84, 3043-3056.

52) Evidence for oxidation at C-3 of the flavonoid C-ring during anthocyanin biosynthesis.
R. W. D. Welford, J. J. Turnbull, T. D. W. Claridge, A. G. Prescott and C. J. Schofield, Chem. Commun., 2001, 1828-1829.

51) Studies on Phytanoyl-CoA 2-hydroxylase and synthesis of Phytanoyl-Coenzyme A.
N. J. Kershaw, M. Mukherji, C. H. MacKinnon, T. D. W. Claridge, B. Odell, A. S. Wierzbicki, M. D. Lloyd and C. J. Schofield, Bioorg. Med. Chem. Lett., 2001, 11, 2545-2548.

50) Regioselective biotransformations of the dinitrile compounds 2-, 3- and 4-(cyanomethyl) benzonitrile by the soil bacterium Rhodococcus rhodochrous LL100-21.
M. R. Dadd, T. D. W. Claridge, R. Walton, A. J. Pettman, and C. J. Knowles, Enzyme Microb. Technol., 2001, 29, 20-27.

49) 10-Helical conformations in oxetane beta-amino acid hexamers.
Timothy D. W. Claridge, Jonathan M. Goodman, Andres Moreno, Donald Angus, Sarah F. Barker, Claude Taillefumier, Mark P. Watterson, and George W. J. Fleet, Tetrahedron. Lett., 2001, 42, 4251-4255.

48) cis- and trans- 3-Azido-Oxetane-2-Carboxylate Scaffolds: Hexamers of Oxetane cis-beta-Amino Acids.
Sarah F. Barker, Donald Angus, Claude Taillefumier, Michael R. Probert, David J. Watkin, Mark P. Watterson, Timothy D. W. Claridge, Natasha L. Hungerford and George W. J. Fleet, Tetrahedron. Lett., 2001, 42, 4247-4250.

47) Studies toward the total synthesis of the cytotoxic sponge alkaloid Pyrinodemin A.
J. E. Baldwin, S. P. Romeril, V. Lee and T. D. W. Claridge, Organic Lett., 2001, 3, 1145-1148.

46) Rotaxane-encapsulation enhances the stability of an azo dye, in solution and when bonded to cellulose.
Michael R. Craig, Michael G. Hutchings, Tim D. W. Claridge, and Harry L. Anderson, Angew. Chem. Int. Ed. Engl., 2001, 40, 1071-1074.

45) Biotransformation of benzonitrile to benzohydroxamic acid by Rhodococcus rhodochrous in the presence of hydroxylamine.
M. R. Dadd, T. D. W. Claridge, A. J. Pettman and C. J. Knowles, Biotech. Lett., 2001, 23, 221-225

44) 207Pb NMR chemical shifts of lead tetracarboxylates.
Jonathan. E. Buston, Tim D. W. Claridge, Stephen J. Heyes, Jeremy L. Bretherton, Mark G. Moloney and Maya Stevenson, Magn. Reson. Chem., 2001, 39, 68-76.

2000

43) Oxidative degradation of bilirubin produces vasoactive compounds.
Kamil R. Kranc, Gail J. Pyne, Limei Tao, Tim D. W. Claridge, David A. Harris, Thomas A. D. Cadoux-Hudson, Jonathan J. Turnbull, Christopher J. Schofield and Joseph F. Clark, Eur. J. Biochem. 2000, 267, 7094-7101.

42) Tetrahydrofuran amino acids: Secondary structure in tetrameric and octameric carbopeptoids derived from a D-allo-5-(aminomethyl)-tetrahydrofuran-2-carboxylic acid.
N. L. Hungerford, T. D. W. Claridge, M. P. Watterson, R. T. Aplin, A. Moreno and G. W. J. Fleet, J. Chem. Soc., Perkin Trans.1, 2000, 3666-3679.

41) Tetrahydrofuran amino acids- versatile building blocks for unnatural biopolymers: lack of secondary structure in oligomeric carbopeptoids derived from a D-galacto-5-(aminomethyl) tetrahydrofuran-2-carboxylic acid.
D E. A. Brittain, M. P. Watterson, T. D. W. Claridge. M. D. Smith and G. W. J. Fleet, J. Chem. Soc., Perkin Trans.1, 2000, 3655-3665.

40) Reaction of clavams with elastase reveals a general method for inhibiting 'serine' enzymes.
R. C. Wilmouth, Y-H. Li, P. A. Wright, T. D. W. Claridge, R. T. Aplin and C. J. Schofield, Tetrahedron, 2000, 56, 5729-5733.

39) Synthesis and crystal structure of a cumulenic quinoidal porphyrin dimer with strong electronic absorption in the infrared.
I. M. Blake, L. H. Rees, T. D. W. Claridge and H. L. Anderson, Angew. Chem. Int. Ed. Engl., 2000, 39, 1818-1821

1999

38) Synthesis of a cyclodextrin azo dye [3]rotaxane as a single isomer.
M. R. Craig, T. D. W. Claridge, M. G. Hutchings and H. L. Anderson, Chem. Commun., 1999, 1537-1538.

37) Studies on the biomimetic synthesis of the manzamine alkaloids.
J. E. Baldwin, T. D. W. Claridge, A. J. Culshaw, F. A. Heupel, V. Lee, D. R. Spring and R. C. Whitehead, Chem. Eur. J., 1999, 5, 3154-3161.

36) Mechanistic insights into the inhibition of serine proteases by monocyclic lactams.
R. C. Wilmouth, S. Kassamally, N. J. Westwood, R. J. Sheppard, T. D. W. Claridge, R. T. Aplin, P. A. Wright, G. J. Pritchard and C. J. Schofield, Biochemistry, 1999, 38, 7989-7998.

35) Absence of secondary structure in a carbopeptoid teramer of a trans-5-aminomethyl-tetrahydrofuran-2-carboxylate.
M. D. Smith, D. D. Long, A. Martin, D. G. Marquess, T. D. W. Claridge, and G. W. J. Fleet, Tetrahedron Lett., 1999, 40, 2191-2194.

34) From sequencamers to foldamers? Tetrameric furanose carbopeptoids from cis- and trans-5-aminomethyl-tetrahydrofuran-2-carboxylates.
D. D. Long, N. L. Hungerford, M. D. Smith, D. E. A. Brittain, D. G. Marquess, T. D. W. Claridge, and G. W. J. Fleet, Tetrahedron Lett., 1999, 40, 2195-2198.

33) An octameric carbopeptoid; secondary structure in octameric ans tetrameric 5-aminomethyl-tetrahydrofuran-2-carboxylates.
T. D. W. Claridge, D. D. Long, N. L. Hungerford, R. T. Aplin, M. D. Smith, D. G. Marquess, and G. W. J. Fleet, Tetrahedron Lett., 1999, 40, 2199-2202.

1998

32) Inhibition of elastase by N-sulfonylaryl beta-lactams: Anatomy of a stable acyl-enzyme complex.
R. C. Wilmouth, N. J. Westwood, K. Anderson, W. Brownlee, T. D. W. Claridge, I. J. Clifton, G. J. Pritchard, R. T. Aplin, C. J. Schofield, Biochemistry, 1998, 37, 17506-17513.

31) A solid phase approach to oligomers of carbohydrate amino-acids: Secondary structure in a trimeric furanose carbopeptoid
D. D. Long, M. D. Smith, D. G. Marquess, T. D. W. Claridge, and G. W. J. Fleet, Tetrahedron. Lett., 1998, 39, 9293-9296.

30) Investigations into the Manzamine Alkaloid Biosynthetic Hypothesis
J. E. Baldwin, T. D. W. Claridge, A. J. Culshaw, F. A. Heupel, V. Lee, D. R. Spring, R. C. Whitehead, R. J. Boughtflower, I. M. Mutton, and R. J. Upton. Angew. Chem. Int. Ed. Engl., 1998, 37, 2661-2663.

29) Secondary structure in oligomers of carbohydrate amino acids
M. D. Smith, T. D. W. Claridge, G. E. Tranter, M. S. P. Sansom, and G. W. J. Fleet, J. Chem. Soc., Chem. Commun., 1998, 2041-2042.

28) Synthesis of oligomers of tetrahydrofuran amino acids: furanose carbopeptoids
M. D. Smith, D. D. Long, D. G. Marquess, T. D. W. Claridge, and G. W. J. Fleet, J. Chem. Soc., Chem. Commun., 1998, 2039-2040.

27) An approach to insulated molecular wires: synthesis of water-soluble conjugated rotaxanes
S. Anderson, R. T. Aplin, T. D. W. Claridge, T. Goodson III, A. C. Maciel, G. Rumbles, J. F. Ryan and H. L. Anderson, J. Chem. Soc., Perkin Trans. 1, 1998, 2383-2397.

26) Synthesis of (2S, 3R, 4S), (2S, 3S, 4R)-Epoxyprolines and Aminohydroxyprolines.
J. K. Robinson, V. Lee, T. D. W. Claridge, J. E. Baldwin and C. J. Schofield, Tetrahedron, 1998, 54, 981-996.

25) Analysis of the conversion of delta-(L-aalpha-aminoadipoyl)-L-cysteinyl-D-alpha-aminobutyrate by active-site mutants of Aspergillus nidulans isopenicillin N synthase.
C. J. Rowe, C. P. Shorrock, T. D. W. Claridge and J. D. Sutherland, Chem. & Biol., 1998, 5, 229-239.

24) 207Pb NMR Chemical Shifts of Aryllead Tricarboxylates.
J. E. H. Buston, T. D. W. Claridge, R. G. Compton and M. G. Moloney, Magn. Reson. Chem., 1998, 36, 140-144.

1997

23) Thermoelectric cooling for NMR Sample Temperature Control.
N. L. Gregory, T. D. W. Claridge and M. Leonard, J. Magn. Reson., 1997, 124, 228-231.

22) An Approach to the Manzamine Alkaloids Modelled on a Biogenetic Theory.
J. E. Baldwin, L. Bischoff, T. D. W. Claridge, F. A. Heupel, D. R. Spring and R. C. Whitehead, Tetrahedron, 1997, 53, 2271-2290.

21) 207Pb, 13C and 1H Nuclear Magnetic Resonance Studies of Lead(IV) Carboxylates in Solution.
T. D. W. Claridge, E. J. Nettleton and M. G. Moloney, Magn. Reson. Chem., 1997, 35, 159-167.

20) Synthesis of 1-Methyl-2-diphenylphosphino-3-(1’-isoquinolyl)indole; an Easily Racemised Ligand giving Insights into Catalytic Asymmetric Allylation.
T. D. W. Claridge, J. M. Long, J. M. Brown, D. Hibbs and M. B. Hursthouse, Tetrahedron, 1997, 53, 4035-4050.

19) Intermediates in the Intermolecular, Asymmetric Heck Arylation of Dihydrofurans.
K. K. Hii, T. D. W. Claridge and J. M. Brown, Angew. Chem. Int. Ed. Engl., 1997, 36, 984-987.

18) Azo-Dye Rotaxanes.
S. Anderson, T. D. W. Claridge and H. L. Anderson, Angew. Chem. Int. Ed. Engl., 1997, 36, 1310-1313.

17) Studies on the reactivity of azetidin-2-ones in phosphate buffer.
N. J. Westwood, C. J. Schofield and T. D. W. Claridge, J. Chem. Soc, Perkin Trans. 1, 1997, 2725-2729.

16) Reversible acylation of Elastase by gama-lactam analogues of beta-lactam inhibitors.
N. J. Westwood, T. D. W. Claridge, P. N. Edwards and C. J. Schofield, Bioorg. Med. Chem. Lett., 1997, 7, 2973-2978.

1996

15) Determination of the Stereochemistry of Four Spirodiastereoisomers by One- and Two-Dimensional NOE studies.
A. Moreno, A. Diaz-Ortiz, E. Diez-Barra, A. de la Hoz, F. Langa, P. Prieto and T. D. W. Claridge, Magn. Reson. Chem., 1996, 34, 52-58.

14) Synthesis and Analysis of Leu-Enkephalin Analogues Containing Reverse Turn Peptidomimetics.
T. D. W. Claridge, C. Hulme, R. J. Kelly, V. Lee, I. A. Nash, and C. J. Schofield, Biorg. Med. Chem. Lett., 1996, 6, 485-490.

13) Inhibition of Human Leukocyte and Porcine Pancreatic Elastase by Homologues of Bovine Pancreatic Trypsin Inhibitor.
J. A. E. Kraunsoe, T. D. W. Claridge and G. Lowe, Biochemistry, 1996, 35, 9090-9096.

12) Structure and Properties of TentaGel Resin Beads: Implications for Combinatorial Library Chemistry.
R. Quarrell, T. D. W. Claridge, G. W. Weaver and G. Lowe, Molecular Diversity, 1996, 1, 223-232.

11) A Biomimetic Approach to the Manzamine Alkaloids.
J. E. Baldwin, T. D. W. Claridge, A. J. Culshaw, F. A. Heupel, S. Smrckova, and R. C. Whitehead, Tetrahedron Lett., 1996, 37, 6919-6922.

1995

10) Structure and Dynamics of Intermediates in Asymmetric Hydrogenation by Rhodium Complexes of (2-Methoxyphenyl)-P-phenyl-P-(2’-diphenylphosphino)ethylphosphine.
J. A. Ramsden, T. D. W. Claridge and J. M. Brown, J. Chem. Soc., Chem. Commun., 1995, 2469-2471.

9) Synthesis and Chemistry of a New P-N Chelating Ligand; (R) and (S)-6-(2’-Diphenylphosphino-1’-napthyl)phenanthridine.
J-M. Valk, T. D.W. Claridge, J. M. Brown, D. Hibbs and M. B. Hursthouse, Tetrahedron: Asymmetry, 1995, 6, 2597-2610.

8) Observation of intermolecular ligand exchange in lead(IV) carboxylates by 1- and 2-D 207Pb NMR spectroscopy.
J. E. H. Buston, T. D. W. Claridge and M. G. Moloney, J. Chem. Soc., Perkin Trans. 2, 1995, 4, 639-641.

 1994

7) Equipment for selective excitation in NMR spectroscopy: enhanced techniques for radio-frequency modulation and digital pulse-shape generation.
N. L. Gregory, T. D. W. Claridge and A. E. Derome, Meas. Sci. Technol., 1994, 5, 1359-1365.

6) A biomimetic approach to the Manzamine Alkaloids; model studies.
J. E. Baldwin, T. D. W. Claridge, F. A. Heupel and R. C. Whitehead, Tetrahedron Lett., 1994, 35, 7829-7832.

5) Comments on the use of a dichromophoric circular dichroism assay for the identification of b-turns in peptides.
J. E. Baldwin, T. D. W. Claridge, C. Hulme, A. Rodger and C. J. Schofield, Int. J. Peptide Protein Res., 1994, 43, 180-183.

1993

4) Revised structures for Tü 1718B and Valclavam
J. E. Baldwin, T. D. W. Claridge, K-C. Goh, J. W. Keeping and C. J. Schofield, Tetrahedron Lett., 1993, 34, 5645-5648.

3) The molecular structure of Dendrotoxin homologues determined by molecular modeling methods and their comparison with the crystal and the 2D-NMR structures.
A. Opalko, T. Claridge, R. Crossley, A. E. Derome, and P. Swaminathan. J. Cell. Biochem., 1993, s17c, 225.

1991

2) Direct observation of a tetrahedral boronic acid-b-lactamase complex using 11B NMR spectroscopy.
J. E. Baldwin, T. D. W. Claridge, A. E. Derome, B. D. Smith, M. Twyman and S. G. Waley. J. Chem. Soc., Chem. Commun., 1991, 573-574.

1) 11B NMR studies of an aryl boronic acid bound to chymotrypsin and subtilisin.
J. E. Baldwin, T. D. W. Claridge, A. E. Derome, C. J. Schofield and B. D. Smith, Bioorg. Med. Chem. Lett, 1991, 1, 9-12.