Gold-catalyzed cascade cyclization-oxidative alkynylation of allenoates.

Symplectic ID: 
90292
Source: 
PubMed
This is the preferred source?: 
1
Last Synced with Symplectic: 
Friday, 11 September, 2026 - 22:31
DOI: 
10.1021/ol102061k
Publication Date: 
Friday, 5 November, 2010
First Page: 
4904
Last Page: 
4907
Keywords: 
Alkynes
Catalysis
Crystallography, X-Ray
Cyclization
Gold
Models, Molecular
Molecular Structure
Naphthalenes
Oxidation-Reduction
Authors: 
Hopkinson, MN
Ross, JE
Giuffredi, GT
Gee, AD
Gouverneur, V
Authors list has been truncated: 
0
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Abstract: 
A gold(I)-catalyzed cascade cyclization-oxidative cross-coupling process has been applied to prepare β-alkynyl-γ-butenolides directly from allenoates and various terminal alkynes. Following an initial gold-catalyzed C-O bond forming allenoate cyclization, a mechanism based on a Au(I)/Au(III) redox cycle has been proposed with Selectfluor acting as the external oxidant.
Journal Title: 
Org Lett
eISSN: 
1523-7052
Volume: 
12
Issue: 
21
ID at Source: 
20936849
Publication Status: 
Published
Open access: 
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SSO preference: 
chem0068