2,5-Disubstituted pyrrolidines: versatile regioselective and diastereoselective synthesis by enamine reduction and subsequent alkylation.

Symplectic ID: 
32443
Source: 
PubMed
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1
Last Synced with Symplectic: 
Monday, 14 September, 2026 - 15:03
DOI: 
10.1039/b303789d
Publication Date: 
Saturday, 7 June, 2003
First Page: 
1838
Last Page: 
1841
Authors: 
Hussaini, SR
Moloney, MG
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0
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Abstract: 
A direct and versatile route enabling the regio- and diastereoselective synthesis of 2,5-disubstituted pyrrolidines by reduction of enamines derived from pyroglutamic acid is reported.
ISSN: 
1477-0520
Journal Title: 
Org Biomol Chem
Volume: 
1
Issue: 
11
ID at Source: 
12945761
Publication Status: 
Published
Open access: 
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SSO preference: 
mmoloney