Symplectic ID:
32512
Source:
PubMed
This is the preferred source?:
1
Last Synced with Symplectic:
Saturday, 5 September, 2026 - 18:43
DOI:
10.1016/s0960-894x(03)00711-x
Publication Date:
Monday, 3 November, 2003
First Page:
3853
Last Page:
3857
Keywords:
Chromatography, High Pressure Liquid
Crystallography, X-Ray
Decarboxylation
Flavonoids
Models, Molecular
Molecular Conformation
Oxygenases
Stereoisomerism
Substrate Specificity
Editors list has been truncated:
Abstract:
Anthocyanidin synthase (ANS), an iron(II) and 2-oxoglutarate (2OG) dependent oxygenase, catalyses the penultimate step in anthocyanin biosynthesis by oxidation of the 2R,3S,4S-cis-leucoanthocyanidins. It has been believed that in vivo the products of ANS are the anthocyanidins. However, in vitro studies on ANS using optically active cis- and trans-leucocyanidin substrates identified cyanidin as only a minor product; instead both quercetin and dihydroquercetin are products with the distribution being dependent on the C-4 stereochemistry of the leucocyanidin substrates.
ISSN:
0960-894X
Journal Title:
Bioorg Med Chem Lett
Volume:
13
Issue:
21
ID at Source:
14552794
Publication Status:
Published
Open access:
Publication Date - Display month part?:
Publication Date - Display day part?:
SSO preference:
cschof
