SuperQuat, (S)-4-benzyl-5,5-dimethyl-oxazolidin-2-one for the asymmetric synthesis of α-substituted-aldehydes

Bull SD, Davies SG, Nicholson RL, Sanganee HJ, Smith AD
8 September 2000
Journal article
Journal:
Tetrahedron Asymmetry
Volume:
11
Issue:
17
,
pp.
3475 - 3479

Reduction of α-substituted-(S)-N-acyl-4-benzyl-5,5-dimethyl-oxazolidin-2-ones with DIBAL-H in CH2Cl2 affords α-substituted aldehydes with no loss of stereochemical integrity at their α-centre. Copyright (C) 2000 Elsevier Science Ltd.

DOI
10.1016/S0957-4166(00)00333-5