Asymmetric Synthesis of (2S,3S)- and (2R,3S)-2,3-Diaminobutanoic Acids, Non-Protein Amino-Acid Diastereomers found in a number of Peptide Antibiotics

Symplectic ID: 
110842
Source: 
Scopus
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Sunday, 26 July, 2026 - 06:01
DOI: 
10.1055/s-1996-5556
Publication Date: 
Monday, 1 January, 1996
First Page: 
621
Last Page: 
622
Authors: 
Burke, AJ
Davies, SG
Hedgecock, CJR
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Abstract: 
(2S,3S)- and (2R,3S)-2,3-diaminobutanoic acids (DABA) are uncommon, naturally occurring amino acid diastereomers found as components of a number of peptide antibiotics. These 2,3-diamino acids have been synthesised by direct and indirect routes, with addition of a chiral lithium amide to tert-butyl crotonate as a key step.
ISSN: 
0936-5214
Journal Title: 
Synlett
Volume: 
1996
Issue: 
7
ID at Source: 
2-s2.0-0001071709
Publication Status: 
Published
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