Enantiospecific Synthesis of Swainsonine, (1S, 2R, 8R, 8aR)-1,2,8-trihydroxyoctahydroindolizine, from D-mannose

Symplectic ID
42325
Source
Scopus
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Sunday, 13 September, 2026 - 15:00
DOI
10.1016/S0040-4039(01)90059-0
Publication Date
Sunday, 1 January, 1984
First Page
1853
Last Page
1856
Authors
Fleet, GWJ
Gough, MJ
Smith, PW
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Abstract
An enantiospecific synthesis of swainsonine from D-mannose is described; the heterocyclic rings of swainsonine are constructed by two intramolecular reductive aminations caused by the catalytic hydrogenation of an azidoaldehyde with 5 equivalents of hydrogen. © 1984.
ISSN
0040-4039
Journal Title
Tetrahedron Letters
Volume
25
Issue
17
ID at Source
2-s2.0-0000448652
Publication Status
Published
Open access
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