The Ag-mediated electrophilic [(18)F]fluorination of an arylboronic ester is reported. This new radiochemical transformation uses [(18)F]selectfluor bis(triflate) in acetone. The process gave 6-[(18)F]fluoro-L-DOPA with a RCY of 19 ± 12% and a specific activity of 2.6 ± 0.3 GBq μmol(-1).
Keywords:
Acetone
,Boronic Acids
,Diazonium Compounds
,Esters
,Fluorine Radioisotopes
,Halogenation
,Levodopa
,Silver
