Rearrangements and racemisation during the synthesis of L-serine derived oxazolidin-2-ones

Bew SP, Bull SD, Davies SG, Savory ED, Watkin DJ

The propensity for N-Boc-4-hydroxymethyl-oxazolidin-2-ones to undergo rapid O-O and N-O carbonyl transfer makes these L-serine derived chiral auxiliaries unsuitable for attachment to polymers. © 2002 Elsevier Science Ltd. All rights reserved.