Betti reaction enables efficient synthesis of 8-hydroxyquinoline inhibitors of 2-oxoglutarate oxygenases

Thinnes CC, Tumber A, Yapp C, Scozzafava G, Yeh T, Chan MC, Tran TA, Hsu K, Tarhonskaya H, Walport LJ, Wilkins SE, Martinez ED
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et al
No abstract available
Keywords:

34 Chemical Sciences

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Dose-Response Relationship, Drug

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Enzyme Inhibitors

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Humans

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Models, Molecular

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Molecular Structure

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Oxygenases

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Oxyquinoline

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Structure-Activity Relationship