Regulation of β-Lactamase Activity by Remote Binding of Heme: Functional Coupling of Unrelated Proteins through Domain Insertion

3101 Biochemistry and Cell Biology

31 Biological Sciences

Biotechnology

Ampicillin

Cephalosporins

Cytochrome b Group

Directed Molecular Evolution

Drug Resistance, Bacterial

Escherichia coli

Escherichia coli Proteins

Heme

Protein Binding

Protein Conformation

Spectrum Analysis

beta-Lactamases