3R-Hydroxymuscarine from L-rhamnose without protection

Mantell SJ, Ford PS, Watkin DJ, Fleet GWJ, Brown D

The synthesis of the muscarine analogue 3R-3-hydroxymuscarine [(2S,3R,4R,5S)-3,4-dihydroxy-tetrahydro-N,N,N,5-tetramethyl-2-furanmethanimium tosylate] from L-rhamnose does not require the use of any protecting group. © 1992 Pergamon Press Ltd.